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The Science Behind Silk Fibroin

China, the birthplace of silk, boasts a sericulture heritage dating back to the Yangshao Culture period (5000-3000 BCE), as evidenced by archaeological discoveries. Techniques for mulberry cultivation, silkworm rearing, silk reeling, and fabric weaving advanced significantly during the Spring and Autumn and Warring States periods, ultimately propelling Chinese silk to global prominence via the ancient Silk Road.

In the modern era, China’s "Belt and Road Initiative" — revitalizing the Silk Road’s legacy through the "New Silk Road Economic Belt" and the "21st Century Maritime Silk Road" — has infused the sericulture and silk industry with fresh challenges and transformative opportunities.

Now, this ancient material is experiencing a scientific renaissance. Through cutting-edge research in polymer materials, silk is unveiling a new realm of possibilities, bridging millennia of tradition with tomorrow’s innovations.

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A Legacy of Exploration Spanning Three Generations
The First Generation:
Professor Tongyin Yu

Professor Tongyin Yu, founding director of the Department of Polymer Science at Fudan University, pioneered China’s polymer science discipline. In his late 60s, Professor Yu spearheaded groundbreaking research in biopolymers, marking a visionary expansion into this emerging field. As later reflected, "The journey of Fudan’s polymer science can be said to encapsulate half the history of China’s polymer science development."

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Silk Fibroin Industrialization: The Foundation
The Second Generation:
Professor Zhengzhong Shao、Professor Chen Xin
(Co-founder/Chief Scientist)

2On August 15, 2002, Professor Shao’s groundbreaking research on silk was published as a brief communication in Nature, marking a new chapter for China’s polymer science on the global academic stage.

From 2002 to the present, silk fibroin—extracted through advanced sericulture—has emerged as an innovative biomaterial within the commercial landscape. Through progressive regulatory standardization and industrial refinement, it has now entered a phase of broadened application scenarios, spanning biomedical engineering, eco-friendly textiles, and advanced cosmetics.

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Silk Fibroin Commercialization Core
The Third Generation:
Dr. Yezhuo Liu
(Founder/Chairman/CTO)

Academic Credentials: Ph.D. in Science from Fudan University, with two decades of research expertise in biomacromolecules.

Standardization Leadership: Contributed to the formulation of national standards for medical device applications of Silk Fibroin.

Key R&D Contributions: Principal investigator for major national programs, including the National Basic Research Program (973 Program), National High-Tech R&D Program (863 Program), and Key Projects under the National Natural Science Foundation of China.

Innovation Output: Published 10+ SCI-indexed papers in internationally renowned journals and holds 20+ patents in silk fibroin extraction, modification, and commercial-scale production technologies.

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Core Ingredient: Silk Fibroin

Silk fibroin, a natural macromolecular protein, has garnered significant attention in the biomedical field in recent years due to its exceptional biocompatibility, biodegradability, and tunable mechanical properties.

We anchored in silk fibroin innovation and driven by the robust R&D capabilities of Fudan University, collaborates globally to realize a vision of sustainable vitality and life-enhancing breakthroughs. "With hearts ablaze with warmth, all life radiates light." In the realm of biomedical materials, we are committed to:
> Establishing a National Flagship Brand that embodies scientific excellence;
> Creating Boundless Societal Value through transformative material solutions;
> Delivering the Promise of Health to advance human well-being worldwide.

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Ingredient Profile

Silk Fibroin: A natural fibrous protein extracted from silk, classified as a high-molecular-weight biopolymer.

Hydrolysis Products: Comprises 18 amino acids, with alanine (Ala), glycine (Gly), and serine (Ser) collectively accounting for over 80% of the total composition.

Unique Structural Configuration: Characterized by an antiparallel β-sheet conformation, which governs its exceptional mechanical stability and biodegradation profile.

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